Migraine in China
Migraine is a prevalent and debilitating CGRP-mediated neurological disorder characterized by recurrent attacks lasting four to 72 hours with four classic symptoms, including one-sided, pulsating headaches of moderate or severe pain intensity that are associated with nausea or vomiting, and/or hypersensitivity to light (photophobia) and sound (phonophobia). The World Health Organization’s (WHO) 2015 Global Burden of Disease Study ranks migraine as the third most prevalent disease in the world  and the seventh highest specific cause of disability worldwide. Migraine affects approximately 9% of the adult population in China, comprising approximately 90 million adults. Approximately 90% of Chinese migraineurs suffer from between one to fourteen headache days per month, and approximately 10% have more than fourteen per month. Approximately 24% of individuals Chinese migraineurs miss more than twenty days of work over a three-month period as a result of migraine . The total indirect cost to Chinese society from lost productivity each year due to migraine is estimated to be about USD$40 billion. Comorbid conditions associated with migraine include depression, anxiety and cardiovascular disease.
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